Regenerative Stem Cell Therapy

Janet D. Pearl, MD, MSc

Suffering From Pain?

We Can Help

Suffering From Pain?

We Can Help

Suffering From Pain?

We Can Help

Suffering From Pain?

We Can Help

Regenerative Stem Cell Therapy

Using Your Own Stem Cells to Relieve Your Pain and Repair Your Body

What is Stem Cell Therapy?

Stem Cell Therapy, is part of a broader, emerging and exciting area of Medicine called “Regenerative Medicine.”   Stem Cell Therapy uses the most potent cells (stem cells) from bone marrow to repair or rebuild injured or degenerated body tissue such as joints, muscles, tendons or ligaments.   The bone marrow is rich in stem cells, growth factors and cell signaling substances.  Stem cells are drawn in a painless way from the pelvic bone and then is injected, along with your concentrated platelet blood product rich in growth factors (Platelet Rich Plasma) into the painful body part, usually using ultrasound guidance for better visualization.  Your Platelet Rich Plasma comes from a simple blood draw, which we spin to separate and extract the platelet rich component.  Sometimes we inject fat with this mixture as it can activate injected stem cells and create a healthy environment for them to multiply as well as for providing a cushion.

Dr. Pearl has been trained by Dr. Joseph Purita at the National Institute of Regenrative Medicine. Dr. Purita is one of the worlds leading experts on Regenerative Medicine and Stem Cell Therapy.

What is a Stem Cell?

Stem cells are “unspecialized” cells that can develop into another type of cell that is required to repair or replace damaged tissue. They are the body’s “repairmen.” We all have stem cells because our own cells are continually dying and being replaced with new cells. Stem cells are present in bone, fat and blood, but are concentrated mostly in the bone marrow, where blood cells are made. Bone marrow (hematopoietic) stem cells usually develop to form whole blood – red blood cells, white blood cells and platelets. However, in other parts of the body, when exposed to the right growth factors and signaled by neighboring cells, these stem cells can develop into other cells, such as bone, cartilage, tendon and ligaments and therefore, can “regenerate” body tissue. They can also reproduce to make more stem cells for more even healing.

So, why does our body not heal itself?

Degeneration often occurs in areas of the body where there is a low blood supply and oxygen level, which do not allow the stem cells to reach the painful area or for cell signaling to take place for healing and regeneration. Regenerative medicine provides the right cells, growth factors and cellular environment to promote healing and regrowth in a body area where blood flow and stem cells could otherwise not reach, especially joints, ligaments, tendons and even discs.

Stem cells

Stem Cell Therapy may be appropriate for you if you have:

What is the process for Stem Cell Therapy?

Stem cell therapy processAlthough stem cells are naturally present in almost all the tissues in varying degrees, the highest concentration occurs in the bone marrow. Stem cells are gathered by aspirating (removing through suction) bone marrow from the back of a patient’s pelvis. This substance is removed from the patient’s pelvis with a tiny needle. Since the patient is given a local anesthetic, only minimal discomfort results from the procedure.

In most cases, 2 oz. (60 cc) of bone marrow aspirate is required. The aspirate includes platelets, mesenchymal stem cells, and other kinds of stem cells used in adult stem cell therapy. After aspiration, the stem cell tissue is separated from non-useful substances and cells via multiple filtration techniques. The bone marrow is placed inside a special container, which in turn is placed into a machine known as a centrifuge. The centrifuge spins the material at a high rate of speed, and this process separates the platelets and stem cells from the remainder of the blood products. It is this concentration of bone marrow—called BMAC, or bone marrow aspiration concentrate that is injected to the site of tissue damage or injury. We use ultrasound and nerve stimulator guidance to increase the accuracy of administration

Once introduced, the platelets then release signal proteins and growth factors which activate the stem cells to divide rapidly. Stem cells by themselves are unable to repair the injured area. These cells have to be properly directed, and platelets perform this function. In effect, stem cells are construction workers and the platelets are their supervisors. Once they are activated, these stem cells perform a variety of valuable functions. Apart from repairing damage to the injured areas, they help damaged cells repair themselves and participate in the repairing process.

Does insurance cover this treatment?

At this point, insurance does not cover this treatment. The treatment is offered only to those willing to pay for it out of pocket.   There are many studies showing success of Stem Cell Therapy, including reductions in pain and regrowth of cartilage in arthritic joints and repair of tendons that were chronically damaged.    However, the studies so far have not been large enough or at the standard that satisfies health care payers.   It is classified as an experimental treatment.  Like any medical treatment, there is the possibility that it will not help.   Some cases of arthritis are too advanced for even stem cell treatment.  We will determine if stem cell therapy might be helpful for you.

Is Stem Cell Therapy right for you?

Although Stem Cell Therapy is considered by some folks to be experimental, various research studies show that regenerative stem cell therapy and platelet rich plasma can provide excellent relief from musculoskeletal pain and ongoing inflammation which occurs in cases of difficult to treat Morton’s neuroma and Plantar Fasciitis.

Why choose Complete Pain Care for your stem cell treatment?


Regenerative Medicine in the News

WSJ regenerative medicine
Sports Illustrated regenerative medicine
Science Daily regenerative medicine
New York Times regenerative medicine
Forbes regenerative medicine
Outside Magazine regenerative medicine
The doctors regenerative medicine

World Renowned Dr. Purita and Dr. Pearl

Dr Purita and Dr. Pearl

Stem Cell Therapy Frequently Asked Questions (FAQ’s):

Why choose Complete Pain Care for your stem cell treatment?

What types of problems can be treated?
  • Hip pain – Hip Joint Arthritis, Labral tears, Greater Trochanteric Bursitis, Ischial Tuberosity Bursitis, Osteonecrosis of the Femoral Head and Sacroiliac Joint Dysfunction
  • Knee pain – Osteoarthritis, Meniscus tears, Patellar Tendonitis/Tendinosis, Quadraceps Strain or Partial Tear, Chondromalacia Patella and Enthesopathy
  • Shoulder pain – Osteoarthritis, Rotator Cuff–Partial Tears, Biceps Tendinosis, Chronic Glenohumeral Ligament Sprains, Acromio-Clavicular Joint Dysfunction and Pain and Levator Scapulae Tendinosis
  • Elbow Pain – Ulnar Collateral Ligament Injury, Distal Biceps Tendon Partial Tear
  • Back pain – Facet Arthritis, Sacroiliac Joint Arthritis, Sacroiliac Joint Dysfunction, Interspinous Ligaments and Iliolumbar Ligaments
  • Joint Pain – Tendonopathy/Tendonosis
  • Foot and Ankle Pain – Ankle osteoarthritis, Chronic Ligament Strains, Chronic Achilles Tendinosis, Chronic Partial Tendon Tear, Morton’s Neuroma and Plantar Fasciitis
  • Wrist and Hand – Chronic Thumb Sprain and Joint Arthritis
How long does Stem Cell Treatment take?

While the bone marrow draw only takes a few minures, the total procedure may take up to 2 to 3 hours.

Who is not a candidate for Stem Cell Therapy or PRP injections?
  1. Patients with active cancers and/or infections.
  2. If bone marrow cells are to be utilized and a patient had a history of a bone marrow derived type of cancer (i.e. lymphoma), this would be considered a relative contra-indication.  However, many times those patients can utilize PRP injections and fat cells, but the ultimate decision maker should be their oncologist.
What should I expect following Stem Cell Therapy?

You will be sore and stiff after the injection which will last for a few days after treatment.   After the numbness wears off, refrain from any activities that increase your discomfort, and refrain from taking anti-inflammatory medications for at least two weeks after treatment. Control your pain with acetaminophen (Tylenol) or medications that your doctor prescribes. Use ice for up to 20 minutes at a time every two to three hours.

Resume any physical therapy regimen about a week after treatment. Your recovery time will depend on the specific condition that is being treated. In all cases, the stem cell injections at the site of your injury will need time to grow your new cells. As the regeneration of new cells proceeds, you should notice a gradual improvement in your level of discomfort, and in your range of motion.

How much does Stem Cell Therapy Cost? Is it covered by insurance?

One of the most common questions that people ask is “how much does Stem Cell Therapy cost?”

These procedures are NOT covered by health insurance plans. But, with financing, many patients can get their painful joints and back treated for a minimum investment. There are a variety of different financing options available, and we can help you find the best one for you.

The total cost will depend on the:

  • severity and extent of your medical condition,
  • how long you have had this problem,
  • number of joints/areas that need to be treated, and
  • how many types of cells are necessary to achieve the results you desire

Each patient’s medical requirement is unique and all our procedures are individualized just for you. Therefore a consultation with our Medical Director (over the phone or face-to-face) is needed to decide your best treatment option and to give you an estimate of the exact cost to you.

To see if you qualify for financing, click the logo below:

What are the Potential Benefits of Treatment?

Patients may see a significant improvement in their symptoms. This may eliminate the need for more aggressive treatments such as long term medication or surgery, as well as a potential remarkable return of function…

Does Stem Cell Therapy hurt?

There may be some pressure at the injection site, but the process is fairly quick. You will be giving a numbing agent to help maintain comfort during your treatment. Most patients say that the marrow draw was tolerable and would do it again.

How do I prepare for Stem Cell Therapy?

Do not take over-the-counter medications that can thin your blood (aspirin, Motrin, Aleve Advil, Naproxen, etc.). Drink as much water as possible on the day of your injection. Arrange for someone to drive you home after treatment.

What is the success rate?

The great majority of patients who responded said that they were satisfied with their treatment and would do it again.  More detailed data from early patients is being collected.

According to the National Institute of Regenerative Medicine, knee and hip patients with severe arthritis who were told they needed a joint replacement surgery have responded as follows:

  • The great majority of knee patients reported more than 50% relief of symptoms.
  • The great majority of hip patients reported more than 50% relief.
What else should I know about Stem Cell Therapy?

 A lot of people are concerned about the reliability and safety of stem cell procedure. Stem cell therapy is safe since your own stem cells are used. This minimizes the risk of problems or complications.

Don’t Suffer Any Longer…

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We’re here to help you with any questions you may have. Please don’t hesitate to reach out to us.




Let’s Talk!

We’re here to help you with any questions you may have. Please don’t hesitate to reach out to us.

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